Determining how Immunosuppressants can be Optimized to Achieve Gene Therapy Durability

Time: 9:30 am
day: Day One AM


• Mitigate initial reaction to transgene to achieve short term durability

• Does it enable patients with prior AAV immunological responses to be doses with gene therapy treatments?

• Is controlling T regulatory cells, and purely T cell depletion the main thing to impact the antibody response?